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Symptoms of PBC. PBC does not always cause symptoms, but some people may experience: bone and joint aches; fatigue (extreme tiredness) itchy skin; ... Bile is a liquid produced inside。

When bile can’t flow properly through your biliary system, it affects all of these organs and vessels. Bile backs up in your bile ducts and organs, irritating the tissues and interfering with。

Bile leakage. Bile is a fluid that helps to digest food by breaking down fat. The liver makes bile which is stored in the gallbladder. Small tubes called bile ducts carry the bile into the small。

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